Pitting of malaria parasites in microfluidic devices mimicking spleen interendothelial slits

Abstract The spleen is a hematopoietic organ that participates in cellular and humoral immunity. It also serves as a quality control mechanism for removing senescent and/or poorly deformable red blood cells (RBCs) from circulation. Pitting is a specialized process by which the spleen extracts partic...

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Bibliographic Details
Main Authors: Aleix Elizalde-Torrent, Claudia Trejo-Soto, Lourdes Méndez-Mora, Marc Nicolau, Oihane Ezama, Melisa Gualdrón-López, Carmen Fernández-Becerra, Tomás Alarcón, Aurora Hernández-Machado, Hernando A. del Portillo
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01568-w