CC-96673 (BMS-986358), an affinity-tuned anti-CD47 and CD20 bispecific antibody with fully functional fc, selectively targets and depletes non-Hodgkin’s lymphoma
Cluster of differentiation 47 (CD47) is a transmembrane protein highly expressed in tumor cells that interacts with signal regulatory protein alpha (SIRPα) and triggers a “don’t eat me” signal to the macrophage, inhibiting phagocytosis and enabling tumor escape from immunosurveillance. The CD47-SIRP...
| প্রধান লেখক: | , , , , , , , , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
Taylor & Francis Group
2024-12-01
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| মালা: | mAbs |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://www.tandfonline.com/doi/10.1080/19420862.2024.2310248 |