Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation

Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation

Here the authors show that active DNA damage response signaling is required both to initiate and maintain meiotic sex chromosome inactivation via a dynamic and reversible process.

Bibliographic Details
Main Authors: Hironori Abe, Yu-Han Yeh, Yasuhisa Munakata, Kei-Ichiro Ishiguro, Paul R. Andreassen, Satoshi H. Namekawa
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34295-5

Internet

https://doi.org/10.1038/s41467-022-34295-5

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