Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer

Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer

Abstract Background Stanniocalcin 1 (STC1) plays an integral role in ovarian cancer (OC). However, the functional role of STC1 in metastasis, lipid metabolism and cisplatin (DDP) chemoresistance in OC is not fully understood. Methods Single-cell sequencing and IHC analysis were performed to reveal S...

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Bibliographic Details
Main Authors: Feikai Lin, Xiaoduan Li, Xinjing Wang, Huizhen Sun, Ziliang Wang, Xipeng Wang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
STC1
Metastasis
Lipid metabolism
DDP chemoresistance
OC
Online Access:https://doi.org/10.1186/s13046-022-02315-3

Internet

https://doi.org/10.1186/s13046-022-02315-3

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