The Human PDZome 2.0: Characterization of a New Resource to Test for PDZ Interactions by Yeast Two-Hybrid

PSD95-disc large-zonula occludens (PDZ) domains are globular modules of 80–90 amino acids that co-evolved with multicellularity. They commonly bind to carboxy-terminal sequences of a plethora of membrane-associated proteins and influence their trafficking and signaling. We previously built a PDZ res...

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Bibliographic Details
Main Authors: Monica Castro-Cruz, Frédérique Lembo, Jean-Paul Borg, Gilles Travé, Renaud Vincentelli, Pascale Zimmermann
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/13/8/737