Increased Ammonium Toxicity in Response to Exogenous Glutamine in Metastatic Breast Cancer Cells

Increased Ammonium Toxicity in Response to Exogenous Glutamine in Metastatic Breast Cancer Cells

Several cancers, including breast cancers, show dependence on glutamine metabolism. The purpose of the present study was to determine the mechanistic basis and impact of differential glutamine metabolism in nonmetastatic and metastatic murine mammary cancer cells. Universally labeled <sup>13&l...

Full description

Bibliographic Details
Main Authors: Violet A. Kiesel, Madeline P. Sheeley, Shawn S. Donkin, Michael K. Wendt, Stephen D. Hursting, Dorothy Teegarden
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Metabolites
Subjects:
glutamine metabolism
metabolic reprogramming
ammonium toxicity
metastasis
breast cancer
Online Access:https://www.mdpi.com/2218-1989/12/5/469

Internet

https://www.mdpi.com/2218-1989/12/5/469

Similar Items