Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates

Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates

Summary: The laminar architecture of the mammalian neocortex depends on the orderly generation of distinct neuronal subtypes by apical radial glia (aRG) during embryogenesis. Here, we identify critical roles for the autism risk gene Foxp1 in maintaining aRG identity and gating the temporal competenc...

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Bibliographic Details
Main Authors: Caroline Alayne Pearson, Destaye M. Moore, Haley O. Tucker, Joseph D. Dekker, Hui Hu, Amaya Miquelajáuregui, Bennett G. Novitch
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720300498

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http://www.sciencedirect.com/science/article/pii/S2211124720300498

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