Neural pathways from hypothalamic orexin neurons to the ventrolateral preoptic area mediate sleep impairments induced by conditioned fear

Neural pathways from hypothalamic orexin neurons to the ventrolateral preoptic area mediate sleep impairments induced by conditioned fear

IntroductionFear and sleep impairments common co-exist, but the underlying mechanisms remain unclear. Hypothalamic orexinergic neurons are involved in the regulation of sleep-wake and fear expression. The ventrolateral preoptic area (VLPO) is an essential brain region to promote sleep, and orexinerg...

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Bibliographic Details
Main Authors: Caifen Ma, Ning Zhou, Kang Ma, Jiandong Niu, Ting Mi, Zhenquan He, Yujun Wen, Chunhong Liu, Zhongyi He, Jianguo Niu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Neuroscience
Subjects:
conditioned fear
sleep impairments
orexin
VLPO
neural pathways
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1122803/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1122803/full

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