A New Bifidobacteria Expression SysTem (BEST) to Produce and Deliver Interleukin-10 in Bifidobacterium bifidum

A New Bifidobacteria Expression SysTem (BEST) to Produce and Deliver Interleukin-10 in Bifidobacterium bifidum

In the last years there has been a growing interest in the use of genetically modified bacteria to deliver molecules of therapeutic interest at mucosal surfaces. Due to the well-recognized probiotic properties of some strains, bifidobacteria represent excellent candidates for the development of live...

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Bibliographic Details
Main Authors: Aurélie Mauras, Florian Chain, Aurélie Faucheux, Pauline Ruffié, Sophie Gontier, Bernhard Ryffel, Marie-José Butel, Philippe Langella, Luis G. Bermúdez-Humarán, Anne-Judith Waligora-Dupriet
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
Bifidobacterium bifidum
microbiota
recombinant bacteria
heterologous expression system
IL-10
low-grade intestinal inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03075/full

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https://www.frontiersin.org/article/10.3389/fmicb.2018.03075/full

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