Disaccharide trehalose in experimental therapies for neurodegenerative disorders: Molecular targets and translational potential

Induction of autophagy is a prospective approach to the treatment of neurodegeneration. In the recent decade, trehalose attracted special attention. It is an autophagy inducer with negligible adverse effects and is approved for use in humans according to FDA requirements. Trehalose has a therapeutic...

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Bibliographic Details
Main Authors: Alexander B. Pupyshev, Tatyana P. Klyushnik, Anna A. Akopyan, Sandeep Kumar Singh, Maria A. Tikhonova
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Pharmacological Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661822003188