Beyond the Warburg Effect: Oxidative and Glycolytic Phenotypes Coexist within the Metabolic Heterogeneity of Glioblastoma

Beyond the Warburg Effect: Oxidative and Glycolytic Phenotypes Coexist within the Metabolic Heterogeneity of Glioblastoma

Glioblastoma (GBM) is the most aggressive primary brain tumor, with a median survival at diagnosis of 16–20 months. Metabolism represents a new attractive therapeutic target; however, due to high intratumoral heterogeneity, the application of metabolic drugs in GBM is challenging. We characterized t...

Full description

Bibliographic Details
Main Authors: Tomás Duraj, Noemí García-Romero, Josefa Carrión-Navarro, Rodrigo Madurga, Ana Ortiz de Mendivil, Ricardo Prat-Acin, Lina Garcia-Cañamaque, Angel Ayuso-Sacido
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
glioblastoma
energy metabolism
glycolysis
oxidative phosphorylation
therapeutics
gene expression profiling
Online Access:https://www.mdpi.com/2073-4409/10/2/202

Internet

https://www.mdpi.com/2073-4409/10/2/202

Similar Items