Human-like PB2 627K influenza virus polymerase activity is regulated by importin-α1 and -α7.

Influenza A viruses may cross species barriers and transmit to humans with the potential to cause pandemics. Interplay of human- (PB2 627K) and avian-like (PB2 627E) influenza polymerase complexes with unknown host factors have been postulated to play a key role in interspecies transmission. Here, w...

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Bibliographic Details
Main Authors: Ben Hudjetz, Gülsah Gabriel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3262014?pdf=render