The difficulty in translating the preclinical success of combined TGFβ and immune checkpoint inhibition to clinical trial
Summary: Immune checkpoint inhibitors (ICIs) have transformed the treatment paradigm for solid tumors. However, even in cancers generally considered ICI-sensitive, responses can vary significantly. Thus, there is an ever-increasing interest in identifying novel means of improving therapeutic respons...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-12-01
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Series: | EBioMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S235239642200562X |