Subclinical diagnosis of cisplatin-induced ototoxicity with biomarkers

Subclinical diagnosis of cisplatin-induced ototoxicity with biomarkers

Abstract A mouse model with cisplatin-induced ototoxicity was used in addition to human samples from the ITMAT Biobank at the University of Pennsylvania. Mouse auditory brainstem responses (ABR), inner ear histology, perilymph cisplatin sampling, and measurement of serum prestin via ELISA were perfo...

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Bibliographic Details
Main Authors: Charles Generotti, Brandon C. Cox, Jarnail Singh, Deborah Hamilton, Erica McKenzie, Bert W. O’Malley, Daqing Li
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23034-x

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https://doi.org/10.1038/s41598-022-23034-x

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