Age-associated global DNA hypermethylation augments the sensitivity of hearts towards ischemia-reperfusion injury

Most pre-clinical studies in cardiac ischemia-reperfusion injury (I/R) are carried out in young or old animals, which does not cater to the adult age in humans who encounter I/R. Not many studies in the literature are available that emphasize the sensitivity of the adult heart to injury from the you...

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Bibliographic Details
Main Authors: Sri Rahavi Boovarahan, Nemat Ali, Abdullah F. AlAsmari, Alaa Alnoor Alameen, Rehan Khan, Gino A. Kurian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.995887/full