Ovarian Cancer Cells in Ascites Form Aggregates That Display a Hybrid Epithelial-Mesenchymal Phenotype and Allows Survival and Proliferation of Metastasizing Cells

Ovarian Cancer Cells in Ascites Form Aggregates That Display a Hybrid Epithelial-Mesenchymal Phenotype and Allows Survival and Proliferation of Metastasizing Cells

Peritoneal metastases are the leading cause of morbidity and mortality in ovarian cancer. Cancer cells float in peritoneal fluid, named ascites, together with a definitely higher number of non neo-neoplastic cells, as single cells or multicellular aggregates. The aim of this work is to uncover the f...

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Bibliographic Details
Main Authors: Sonia Capellero, Jessica Erriquez, Chiara Battistini, Roberta Porporato, Giulia Scotto, Fulvio Borella, Maria F. Di Renzo, Giorgio Valabrega, Martina Olivero
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
ovarian cancer
ascites
PAX8
αSMA
fibronectin
epithelial-mesenchymal phenotype
Online Access:https://www.mdpi.com/1422-0067/23/2/833

Internet

https://www.mdpi.com/1422-0067/23/2/833

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