Epigenomic landscape study reveals molecular subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinomaResearch in context

Epigenomic landscape study reveals molecular subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinomaResearch in context

Summary: Background: Epstein-Barr virus (EBV) latent infection is associated with genome-wide epigenomic changes in several malignancies, but its role in epigenetic dysregulation remains unclear in nasopharyngeal carcinoma (NPC). Methods: To investigate EBV-associated epigenetic dysregulation, we p...

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Bibliographic Details
Main Authors: Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Lihua Tao, Kui Fat Chan, Stewart Yuk Tung, Roger Kai Cheong Ngan, Wai Tong Ng, Anne Wing-Mui Lee, Chun Chung Yau, Dora Lai-Wan Kwong, Victor Ho-Fun Lee, Ka-On Lam, Jiayan Liu, Honglin Chen, Wei Dai, Maria Li Lung
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:EBioMedicine
Subjects:
Epstein-Barr virus
Nasopharyngeal carcinoma
Host-virus interaction
Whole-genome bisulfite sequencing
Chromatin accessibility
Tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422005394

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http://www.sciencedirect.com/science/article/pii/S2352396422005394

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