The evolving role of long noncoding RNA HIF1A-AS2 in diabetic retinopathy: a cross-link axis between hypoxia, oxidative stress and angiogenesis via MAPK/VEGF-dependent pathway

The evolving role of long noncoding RNA HIF1A-AS2 in diabetic retinopathy: a cross-link axis between hypoxia, oxidative stress and angiogenesis via MAPK/VEGF-dependent pathway

Background Diabetic retinopathy (DR) signifies a frequent serious diabetic complication influencing retinal structure and function. Dysregulation of lncRNAs drives a wide array of human diseases especially diabetes; thus, we aimed to study lncRNA HIF1A-AS2 role and its interplay with hypoxia, oxidat...

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Bibliographic Details
Main Authors: Marwa Mohamed Atef, Noha M. Shafik, Yasser Mostafa Hafez, Mona Mohamed Watany, Amal Selim, Heba M. Shafik, Omnia Safwat El-Deeb
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Redox Report
Subjects:
Diabetic retinopathy
HIF1A-AS2
HIF-1α
VEGF
MAPK
endoglin
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2022.2050086

Internet

https://www.tandfonline.com/doi/10.1080/13510002.2022.2050086

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