CASPIAN: A method to identify chromatin topological associated domains based on spatial density cluster

CASPIAN: A method to identify chromatin topological associated domains based on spatial density cluster

With the development of Hi-C technology, the detection of topologically associated domains (TADs) boundaries plays an important role in exploring the relationship between gene structure and expression. However, a method that can identify accurate TAD boundaries from the Hi-C contact matrix with diff...

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Bibliografske podrobnosti
Main Authors: Haiyan Gong, Yi Yang, Xiaotong Zhang, Minghong Li, Sichen Zhang, Yang Chen
Format: Article
Jezik:English
Izdano: Elsevier 2022-01-01
Serija:Computational and Structural Biotechnology Journal
Teme:
Hi-C
Chromatin structure
TAD
Spatial distance
Cluster
Online dostop:http://www.sciencedirect.com/science/article/pii/S2001037022003932

Internet

http://www.sciencedirect.com/science/article/pii/S2001037022003932

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