Vascular network expansion, integrity of blood–brain interfaces, and cerebrospinal fluid cytokine concentration during postnatal development in the normal and jaundiced rat

Vascular network expansion, integrity of blood–brain interfaces, and cerebrospinal fluid cytokine concentration during postnatal development in the normal and jaundiced rat

Abstract Background Severe neonatal jaundice resulting from elevated levels of unconjugated bilirubin in the blood induces dramatic neurological impairment. Central oxidative stress and an inflammatory response have been associated with the pathophysiological mechanism. Cells forming the blood–brain...

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Bibliographic Details
Main Authors: Sandrine Blondel, Nathalie Strazielle, Amel Amara, Rainui Guy, Christine Bain, Alix Rose, Laurent Guibaud, Claudio Tiribelli, Silvia Gazzin, Jean-François Ghersi-Egea
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Fluids and Barriers of the CNS
Subjects:
Blood–brain barrier
Blood–CSF barrier
Choroid plexus
Cerebrospinal fluid
Neurovascular
Postnatal development hyperbilirubinemia
Online Access:https://doi.org/10.1186/s12987-022-00332-0

Internet

https://doi.org/10.1186/s12987-022-00332-0

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