Discrimination of three mutational events that result in a disruption of the R122 primary autolysis site of the human cationic trypsinogen (PRSS1) by denaturing high performance liquid chromatography

Discrimination of three mutational events that result in a disruption of the R122 primary autolysis site of the human cationic trypsinogen (PRSS1) by denaturing high performance liquid chromatography

<p>Abstract</p> <p>Background</p> <p>R122, the primary autolysis site of the human cationic trypsinogen (PRSS1), constitutes an important "self-destruct" or "fail-safe" defensive mechanism against premature trypsin activation within the pancreas. Dis...

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Bibliographic Details
Main Authors: Férec Claude, Raguénès Odile, Quéré Isabelle, Chen Jian-Min, Le Maréchal Cedric, Auroux Jean
Format: Article
Language:English
Published: BMC 2001-11-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/2/19

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http://www.biomedcentral.com/1471-2156/2/19

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