Rifaximin Improves Spatial Learning and Memory Impairment in Rats with Liver Damage-Associated Neuroinflammation

Rifaximin Improves Spatial Learning and Memory Impairment in Rats with Liver Damage-Associated Neuroinflammation

Patients with non-alcoholic fatty liver disease (NAFLD) may show mild cognitive impairment. Neuroinflammation in the hippocampus mediates cognitive impairment in rat models of minimal hepatic encephalopathy (MHE). Treatment with rifaximin reverses cognitive impairment in a large proportion of cirrho...

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Bibliographic Details
Main Authors: Paola Leone, Gergana Mincheva, Tiziano Balzano, Michele Malaguarnera, Vicente Felipo, Marta Llansola
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
hepatic encephalopathy
mild liver damage
rifaximin
microglia
NMDA receptor
spatial learning and memory
Online Access:https://www.mdpi.com/2227-9059/10/6/1263

Internet

https://www.mdpi.com/2227-9059/10/6/1263

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