Orexin neurons play contrasting roles in itch and pain neural processing via projecting to the periaqueductal gray
Abstract Pain and itch are recognized as antagonistically regulated sensations; pain suppresses itch, whilst pain inhibition enhances itch. The neural mechanisms at the central nervous system (CNS) underlying these pain-itch interactions still need to be explored. Here, we revealed the contrasting r...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-05997-x |