Synthesis of New Isoxazolidine Derivatives Utilizing the Functionality of <i>N</i>-Carbonylpyrazol-Linked Isoxazolidines

Synthesis of New Isoxazolidine Derivatives Utilizing the Functionality of <i>N</i>-Carbonylpyrazol-Linked Isoxazolidines

Using Ni(II) as the catalyst, electron-deficient 3,5-dimethylacryloylpyrazole olefin was reacted with <i>C</i>,<i>N</i>-diarylnitrones alone for 10 min to prepare novel five-member heterocyclic products, 4-3,5-dimethylacryloylpyrazole isoxazolidines with 100% regioselectivity...

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Bibliographic Details
Main Authors: Xixian Cao, Jun You, Yunze Wang, Yanchao Yu, Wenju Wu, Yifang Liang
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Molecules
Subjects:
3,5-dimethylpyrazole
isoxazolidine
1,3-dipolar cycloaddition
nucleophilic substitution
reduction reaction
Online Access:https://www.mdpi.com/1420-3049/29/15/3454

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https://www.mdpi.com/1420-3049/29/15/3454

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