Chemical profiling and evaluation of toxicological, antioxidant, anti-inflammatory, anti-nociceptive and tyrosinase inhibitory potential of Portulacaria afra using in-vitro, in-vivo and in-silico studies

Chemical profiling and evaluation of toxicological, antioxidant, anti-inflammatory, anti-nociceptive and tyrosinase inhibitory potential of Portulacaria afra using in-vitro, in-vivo and in-silico studies

Portulacaria afra Jacq (Portulacaceae) is a medicinal plant used traditionally in the treatment of pain and inflammation. This study aimed to evaluate the phytochemical composition, toxicity, antinociceptive, and enzyme inhibition potential of P. afra. The methanol extract (PAME) was prepared throug...

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Bibliographic Details
Main Authors: Sobia Tabassum, Saeed Ahmad, Kashif ur Rehman Khan, Baber Ali, Faisal Usman, Qaiser Jabeen, Muhammad Sajid-ur-Rehman, Maqsood Ahmed, Hafiz Muhammad Zubair, Luay Alkazmi, Gaber El-Saber Batiha, Qamar-uz- Zaman, Abdul Basit
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Arabian Journal of Chemistry
Subjects:
Portulacaria afra
RP-UHPLC-MS
Acute oral toxicity
Anti-nociceptive
Anti-inflammatory
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223002460

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http://www.sciencedirect.com/science/article/pii/S1878535223002460

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