Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection

Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection

Abstract Escherichia coli is the most common gram-negative pathogenic bacterium causing meningitis. It penetrates the blood–brain barrier (BBB) and activates nuclear factor kappa B (NF-κB) signaling, which are vital events leading to the development of meningitis. Long non-coding RNAs (lncRNAs) have...

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Bibliographic Details
Main Authors: Bojie Xu, Ruicheng Yang, Bo Yang, Liang Li, Jiaqi Chen, Jiyang Fu, Xinyi Qu, Dong Huo, Chen Tan, Huanchun Chen, Zhong Peng, Xiangru Wang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Molecular Brain
Subjects:
LncC11orf54-1
Neuroinflammation
Brain microvascular endothelial cells
NF-κB signaling
Meningitic Escherichia coli
Blood–brain barrier
Online Access:https://doi.org/10.1186/s13041-021-00890-8

Internet

https://doi.org/10.1186/s13041-021-00890-8

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