Neutrophil-Derived Myeloperoxidase Facilitates Both the Induction and Elicitation Phases of Contact Hypersensitivity

Neutrophil-Derived Myeloperoxidase Facilitates Both the Induction and Elicitation Phases of Contact Hypersensitivity

BackgroundAllergic contact dermatitis (ACD) is a common skin disorder affecting an estimated 15-20% of the general population. The mouse model of ACD is contact hypersensitivity (CHS), which consists of two phases: induction and elicitation. Although neutrophils are required for both CHS disease pha...

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Bibliographic Details
Main Authors: Anna Strzepa, Cody J. Gurski, Landon J. Dittel, Marian Szczepanik, Kirkwood A. Pritchard, Bonnie N. Dittel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
contact hypersensitivity
interleukin 1β
myeloperoxidase
neutrophil
vascular permeability
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.608871/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.608871/full

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