LncRNA NEAT1 promotes MPP+ induced injury of PC12 cells and accelerates the progression of Parkinson's disease in mice through FUS mediated inhibition of PI3K/AKT/mTOR signalling pathway

LncRNA NEAT1 promotes MPP+ induced injury of PC12 cells and accelerates the progression of Parkinson's disease in mice through FUS mediated inhibition of PI3K/AKT/mTOR signalling pathway

Long noncoding RNA nuclear-enriched abundant transcript 1 (NEAT1) is involved in the progression of Parkinson's disease (PD), but the specific regulatory role needs further exploration. This study showed that the expression of NEAT1 was upregulated in the cerebrospinal fluid (CSF) and periphera...

Полное описание

Библиографические подробности
Главные авторы: Yonghui Wang, Zhuo Li, Jiwen Li, Chao Sun
Формат: Статья
Язык:English
Опубликовано: Elsevier 2024-06-01
Серии:Experimental Gerontology
Предметы:
Parkinson
lncRNA NEAT1
FUS
The PI3K/AKT/mTOR signalling pathway
Autophagy
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S0531556524000780

Internet

http://www.sciencedirect.com/science/article/pii/S0531556524000780

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