LncRNA NEAT1 promotes MPP+ induced injury of PC12 cells and accelerates the progression of Parkinson's disease in mice through FUS mediated inhibition of PI3K/AKT/mTOR signalling pathway

LncRNA NEAT1 promotes MPP+ induced injury of PC12 cells and accelerates the progression of Parkinson's disease in mice through FUS mediated inhibition of PI3K/AKT/mTOR signalling pathway

Long noncoding RNA nuclear-enriched abundant transcript 1 (NEAT1) is involved in the progression of Parkinson's disease (PD), but the specific regulatory role needs further exploration. This study showed that the expression of NEAT1 was upregulated in the cerebrospinal fluid (CSF) and periphera...

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Bibliographic Details
Main Authors: Yonghui Wang, Zhuo Li, Jiwen Li, Chao Sun
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Experimental Gerontology
Subjects:
Parkinson
lncRNA NEAT1
FUS
The PI3K/AKT/mTOR signalling pathway
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556524000780

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