SPLUNC1 regulates cell progression and apoptosis through the miR-141-PTEN/p27 pathway, but is hindered by LMP1.

SPLUNC1 regulates cell progression and apoptosis through the miR-141-PTEN/p27 pathway, but is hindered by LMP1.

Little is known about the role of the host defensive protein short palate, lung and nasal epithelium clone 1 (SPLUNC1) in the carcinogenesis of nasopharyngeal carcinoma (NPC). Here we report that SPLUNC1 plays a role at a very early stage of NPC carcinogenesis. SPLUNC1 regulates NPC cell proliferati...

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Detalles Bibliográficos
Autores principales: Pan Chen, Xiaofang Guo, Houde Zhou, Wenling Zhang, Zhaoyang Zeng, Qianjin Liao, Xiayu Li, Bo Xiang, Jianbo Yang, Jian Ma, Ming Zhou, Shuping Peng, Juanjuan Xiang, Xiaoling Li, Colvin Wanshura L E, Wei Xiong, James B McCarthy, Guiyuan Li
Formato: Artículo
Lenguaje:English
Publicado: Public Library of Science (PLoS) 2013-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3589440?pdf=render

Internet

http://europepmc.org/articles/PMC3589440?pdf=render

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