Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone
ABSTRACT Despite the clinical relevance, dengue virus (DENV) research has been hampered by the absence of robust reverse genetic systems to manipulate the viral serotypes for propagation and generation of mutant viruses. In this article, we describe application of an infectious clone system for DENV...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-02-01
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Series: | mSphere |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mSphere.00380-16 |