Molecular Signatures of Human Regulatory T Cells in Colorectal Cancer and Polyps

Molecular Signatures of Human Regulatory T Cells in Colorectal Cancer and Polyps

Regulatory T cells (Tregs), a subset of CD4+ or CD8+ T cells, play a pivotal role in regulating immune homeostasis. An increase in Tregs was reported in many tumors to be associated with immune suppression and evasion in cancer patients. Despite the importance of Tregs, the molecular signatures that...

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Bibliographic Details
Main Authors: Nor Adzimah Johdi, Kamel Ait-Tahar, Ismail Sagap, Rahman Jamal
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
regulatory T cells
colorectal cancer
gene expression
immune suppression
interleukin
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00620/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00620/full

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