Increased Sociability in Mice Lacking Intergenic Dlx Enhancers

Increased Sociability in Mice Lacking Intergenic Dlx Enhancers

The Dlx homeodomain transcription factors play important roles in the differentiation and migration of GABAergic interneuron precursors. The mouse and human genomes each have six Dlx genes organized into three convergently transcribed bigene clusters (Dlx1/2, Dlx3/4, and Dlx5/6) with cis-regulatory...

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Bibliographic Details
Main Authors: Siavash Fazel Darbandi, Crystal Esau, Cindy Lesage-Pelletier, Simon Monis, Luc Poitras, Man Yu, Sofia Perin, Gary Hatch, Marc Ekker
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Neuroscience
Subjects:
autism
development
Dlx
GABA
gene regulation
Williams–Beuren syndrome
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.718948/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.718948/full

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