Identifying mutation regions for closely related individuals without a known pedigree

<p>Abstract</p> <p>Background</p> <p>Linkage analysis is the first step in the search for a disease gene. Linkage studies have facilitated the identification of several hundred human genes that can harbor mutations leading to a disease phenotype. In this paper, we study...

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Bibliographic Details
Main Authors: Cui Wenjuan, Wang Lusheng
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/146