Impact of Sirolimus as a Primary Immunosuppressant on Myocardial Fibrosis and Diastolic Function Following Heart Transplantation

Impact of Sirolimus as a Primary Immunosuppressant on Myocardial Fibrosis and Diastolic Function Following Heart Transplantation

Background Myocardial fibrosis is an important contributor for development of diastolic dysfunction. We investigated the impact of sirolimus as primary immunosuppression on diastolic dysfunction and fibrosis progression among heart transplantation recipients. Methods and Results In 100 heart transpl...

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Bibliographic Details
Main Authors: Hilmi Alnsasra, Rabea Asleh, Jae K. Oh, Joseph J. Maleszewski, Amir Lerman, Takumi Toya, Krishnaswamy Chandrasekaran, Melanie C. Bois, Sudhir S. Kushwaha
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
diastolic dysfunction
myocardial fibrosis
sirolimus
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.018186

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.018186

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