Enhanced actin pedestal formation by enterohemorrhagic Escherichia coli O157:H7 adapted to the mammalian host.

Enhanced actin pedestal formation by enterohemorrhagic Escherichia coli O157:H7 adapted to the mammalian host.

Upon intestinal colonization, enterohemorrhagic Escherichia coli (EHEC) induces epithelial cells to generate actin pedestals beneath bound bacteria, lesions that promote colonization. To induce pedestals, EHEC utilizes a type III secretion system to translocate into the mammalian cell bacterial effe...

Full description

Bibliographic Details
Main Authors: Michael John Brady, Padhma eRadhakrishnan, Hui eLiu, Loranne eMagoun, Kenan C Murphy, Jean eMukherjee, Arthur eDonohue-Rolfe, Saul eTzipori, John M Leong
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Microbiology
Subjects:
translocation
actin assembly
EHEC
host-adaptation
Intimin
Tir
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00226/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00226/full

Similar Items