Ischemic postconditioning ameliorates acute kidney injury induced by limb ischemia/reperfusion via transforming TLR4 and NF-κB signaling in rats

Ischemic postconditioning ameliorates acute kidney injury induced by limb ischemia/reperfusion via transforming TLR4 and NF-κB signaling in rats

Abstract Background The present study investigated the influence of ischemic postconditioning (I-postC) on the adjustment of renal injury after limb ischemia-reperfusion (I/R) injury, to elucidate the mechanisms of the Toll-like receptor 4 (TLR 4)/NF-κB signaling pathway using histopathological and...

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Bibliographic Details
Main Authors: Zhongdi Liu, Wei Huang, Yifan Chen, Zhe Du, Fengxue Zhu, Tianbing Wang, Baoguo Jiang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Limb ischemia
Reperfusion injury
Kidney
Ischemic postconditioning
Online Access:https://doi.org/10.1186/s13018-021-02565-5

Internet

https://doi.org/10.1186/s13018-021-02565-5

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