Novel methylation specific real-time PCR test for the diagnosis of Klinefelter syndrome

Novel methylation specific real-time PCR test for the diagnosis of Klinefelter syndrome

The aim of this study was to design a molecular assay for the diagnosis of Klinefelter syndrome (KS), based on the detection of supernumerary X-chromosomes (X-chs). DNA was extracted from peripheral blood samples of twenty-six 47,XXY males; two 46,XY/47,XXY males; twenty-two 46,XY males; and 15 fema...

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Bibliographic Details
Main Authors: Akanksha Mehta, Anna Mielnik, Peter N Schlegel, Darius A Paduch
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-10-01
Series:Asian Journal of Andrology
Subjects:
DNA methylation; Klinefelter syndrome; mosaicism; polymerase chain reaction
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=5;spage=684;epage=688;aulast=Mehta

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=5;spage=684;epage=688;aulast=Mehta

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