Identification of a novel somatic mutation of POU6F2 by whole‐genome sequencing in prolactinoma

Identification of a novel somatic mutation of POU6F2 by whole‐genome sequencing in prolactinoma

Abstract Background Pituitary adenomas (PAs) are one of the most common intracranial tumors; approximately half of PAs are prolactin (PRL)‐secreting PAs (prolactinomas). The genetic alterations prevalent in prolactinomas are unknown. Methods Here, we present a patient with an extremely aggressive an...

Full description

Bibliographic Details
Main Authors: Yazhou Miao, Chuzhong Li, Jing Guo, Hongyun Wang, Lei Gong, Weiyan Xie, Yazhuo Zhang
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
mutation
POU6F2
prolactinoma
whole‐genome sequencing
Online Access:https://doi.org/10.1002/mgg3.1022

Internet

https://doi.org/10.1002/mgg3.1022

Similar Items