Bone marrow mesenchymal stem cell-derived small extracellular vesicles promote liver regeneration via miR-20a-5p/PTEN

Bone marrow mesenchymal stem cell-derived small extracellular vesicles promote liver regeneration via miR-20a-5p/PTEN

Balancing hepatocyte death and proliferation is key to non-transplantation treatments for acute liver failure (ALF), which has a high short-term mortality rate. Small extracellular vesicles (sEVs) may act as mediators in the repair of damaged liver tissue by mesenchymal stem cells (MSCs). We aimed t...

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Bibliographic Details
Main Authors: Jing Zhang, Juan Gao, Xianlong Li, Dengna Lin, Zhihui Li, Jialei Wang, Junfeng Chen, Zhiliang Gao, Bingliang Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
acute liver failure
extracellular vesicles
liver regeneration
mesenchymal stem cells
miRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1168545/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1168545/full

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