Ivermectin metabolites reduce Anopheles survival

Abstract Ivermectin mass drug administration to humans or livestock is a potential vector control tool for malaria elimination. The mosquito-lethal effect of ivermectin in clinical trials exceeds that predicted from in vitro laboratory experiments, suggesting that ivermectin metabolites have mosquit...

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Bibliographic Details
Main Authors: Kevin C. Kobylinski, Phornpimon Tipthara, Narenrit Wamaket, Sittinont Chainarin, Rattawan Kullasakboonsri, Patchara Sriwichai, Siriporn Phasomkusolsil, Borimas Hanboonkunupakarn, Podjanee Jittamala, Renia Gemmell, John Boyle, Stephen Wrigley, Jonathan Steele, Nicholas J. White, Joel Tarning
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34719-2