New Insight into the Concanavalin A-Induced Apoptosis in Hepatocyte of an Animal Model: Possible Involvement of Caspase-Independent Pathway

New Insight into the Concanavalin A-Induced Apoptosis in Hepatocyte of an Animal Model: Possible Involvement of Caspase-Independent Pathway

Concanavalin A (Con A) is known to be a T-cell mitogen and has been shown to induce hepatitis in mice through the triggering of conventional T cells and NKT cells. However, it remains unknown whether Con A itself can directly induce rapid hepatocyte death in the absence of a functional immune system...

Full description

Bibliographic Details
Main Authors: Xiangli Zhao, Cheng Fu, Lingjuan Sun, Hao Feng, Peiling Xie, Meng Wu, Xiaosheng Tan, Gang Chen
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
concanavalin A
hepatocyte
cell death
apoptosis
liver injury
Online Access:https://www.mdpi.com/1420-3049/28/3/1312

Internet

https://www.mdpi.com/1420-3049/28/3/1312

Similar Items