PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis

PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis

Abstract Background Breast cancer is the leading cause of cancer death for women worldwide. Most of the breast cancer death are due to disease recurrence and metastasis. Increasingly accumulating evidence indicates that mitochondria play key roles in cancer progression and metastasis. Our recent stu...

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Bibliographic Details
Main Authors: Yang Wang, Jieyi Wang, Lan Chen, Zhuo Chen, Tong Wang, Shuting Xiong, Tong Zhou, Guang Wu, Licai He, Jiawei Cao, Min Liu, Hongzhi Li, Haihua Gu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cancer Cell International
Subjects:
PRRG4
Mitochondrial DNA
Src
STAT3
POLG
Breast cancer
Online Access:https://doi.org/10.1186/s12935-023-03178-0

Internet

https://doi.org/10.1186/s12935-023-03178-0

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