HPLC and TLC chromatographic methods for simultaneous determination of binary mixture of isoconazole nitrate and diflucortolone valerate

HPLC and TLC-densitometric methods were used to determine a binary mixture of isoconazole (ISO) and diflucortolone (DIF). For HPLC method a rapid separation could be achieved on a C18 column using mobile phase of 80% acetonitrile–20% methanol. The components were monitored at 230 nm over a concentra...

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Bibliographic Details
Main Authors: Mohamed R. El-Ghobashy, Yasmin M. Fayez, Zeinab M. Goda, Mostafa A. Shehata
Format: Article
Language:English
Published: Faculty of Pharmacy, Cairo University 2016-06-01
Series:Bulletin of Faculty of Pharmacy Cairo University
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110093115000514