HPLC and TLC chromatographic methods for simultaneous determination of binary mixture of isoconazole nitrate and diflucortolone valerate

HPLC and TLC chromatographic methods for simultaneous determination of binary mixture of isoconazole nitrate and diflucortolone valerate

HPLC and TLC-densitometric methods were used to determine a binary mixture of isoconazole (ISO) and diflucortolone (DIF). For HPLC method a rapid separation could be achieved on a C18 column using mobile phase of 80% acetonitrile–20% methanol. The components were monitored at 230 nm over a concentra...

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Bibliographic Details
Main Authors: Mohamed R. El-Ghobashy, Yasmin M. Fayez, Zeinab M. Goda, Mostafa A. Shehata
Format: Article
Language:English
Published: Faculty of Pharmacy, Cairo University 2016-06-01
Series:Bulletin of Faculty of Pharmacy Cairo University
Subjects:
Isoconazole
Diflucortolone
HPLC
TLC-densitometry
Online Access:http://www.sciencedirect.com/science/article/pii/S1110093115000514

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