TGF-β in T Cell Biology: Implications for Cancer Immunotherapy

Transforming Growth Factor beta (TGF-β) is a pleiotropic cytokine produced in large amounts within cancer microenvironments that will ultimately promote neoplastic progression, notably by suppressing the host’s T-cell immunosurveillance. This effect is mostly due to the well-known...

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Bibliographic Details
Main Authors: Amina Dahmani, Jean-Sébastien Delisle
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/6/194