Aging does not enhance experimental cigarette smoke-induced COPD in the mouse.
It has been proposed that the development of COPD is driven by premature aging/premature senescence of lung parenchyma cells. There are data suggesting that old mice develop a greater inflammatory and lower anti-oxidant response after cigarette smoke compared to young mice, but whether these differe...
Autori principali: | , , , , |
---|---|
Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Public Library of Science (PLoS)
2013-01-01
|
Serie: | PLoS ONE |
Accesso online: | http://europepmc.org/articles/PMC3732225?pdf=render |