Aging does not enhance experimental cigarette smoke-induced COPD in the mouse.

It has been proposed that the development of COPD is driven by premature aging/premature senescence of lung parenchyma cells. There are data suggesting that old mice develop a greater inflammatory and lower anti-oxidant response after cigarette smoke compared to young mice, but whether these differe...

Descrizione completa

Dettagli Bibliografici
Autori principali: Steven Zhou, Joanne L Wright, Joseph Liu, Don D Sin, Andrew Churg
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3732225?pdf=render