Assessment of Mechanisms Involved in Antinociception Produced by the Alkaloid Caulerpine

Assessment of Mechanisms Involved in Antinociception Produced by the Alkaloid Caulerpine

In previous works we showed that oral administration of caulerpine, a bisindole alkaloid isolated from algae of the genus Caulerpa, produced antinociception when assessed in chemical and thermal models of nociception. In this study, we evaluated the possible mechanism of action of this alkaloid in m...

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Bibliographic Details
Main Authors: Luiz Henrique Agra Cavalcante-Silva, Maria Alice Pimentel Falcão, Ana Carolina Santana Vieira, Max Denisson Maurício Viana, João Xavier de Araújo-Júnior, Jéssica Celestino Ferreira Sousa, Tania Maria Sarmento da Silva, José Maria Barbosa-Filho, François Noël, George Emmanuel C. de Miranda, Bárbara Viviana de Oliveira Santos, Magna Suzana Alexandre-Moreira
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
caulerpine
antinociception
adrenergic pathway
serotonergic pathway
Online Access:http://www.mdpi.com/1420-3049/19/9/14699

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http://www.mdpi.com/1420-3049/19/9/14699

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