Sodium houttuyfonate effectively treats acute pulmonary infection of Pseudomonas aeruginosa by affecting immunity and intestinal flora in mice

Sodium houttuyfonate effectively treats acute pulmonary infection of Pseudomonas aeruginosa by affecting immunity and intestinal flora in mice

IntroductionPseudomonas aeruginosa is a major nosocomial pathogen that frequently causes ventilator-associated pneumonia in specific populations. Sodium houttuyfonate (SH) has shown mild antibacterial activity against P. aeruginosa in vitro, but the mechanism of potent antimicrobial activity of SH a...

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Bibliographic Details
Main Authors: Tian Zhuang, Mengxue Hu, Jian Wang, Longfei Mei, Xiaoxiao Zhu, Haitao Zhang, Feng Jin, Jing Shao, Tianming Wang, Changzhong Wang, Xiaojia Niu, Daqiang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Sodium houttuyfonate
Pseudomonas aeruginosa
inflammatory factor
TLR4/NF-κB pathway
intestinal flora
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1022511/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.1022511/full

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