Paracrine Interleukin 6 Induces Cerebral Remodeling at Early Stages After Unilateral Common Carotid Artery Occlusion in Mice

AimsCarotid artery disease is frequent and can result in chronic modest hypoperfusion of the brain. If no transient ischemic attack or stroke occur, it is classified asymptomatic. In the long-term, though, it can lead to cognitive impairment. Fostering cerebral remodeling after carotid artery occlus...

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Main Authors: Melanie T. C. Kuffner, Stefan P. Koch, Marieluise Kirchner, Susanne Mueller, Janet Lips, Jeehye An, Philipp Mertins, Ulrich Dirnagl, Matthias Endres, Philipp Boehm-Sturm, Christoph Harms, Christian J. Hoffmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.805095/full